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Fructosamine

Fructosamine 

Synonym - Specimen - Reference Value - Method - Description - Indication - Interpretation 



Synonym           : Glycated albumin 
Specimen           : Serum (1 mL) 
Reference Value : Normal 174-286 micron mol/L 
                      Diabetic   controlled 210 - 421 micron mol/L 
                      Uncontrolled 268 - 870 micron mol/L 

Method                 : Spectrophotometry 

Description 

Fructosamine is the result of covalent linkage between glucose and albumin or other proteins.
Similar to glycated Hemoglobin , Fractosamine can be used to monitor long-term control of glucose in diabetics . 
It has a shorter half-life than glycated hemoglobin and is thought to be more sensitive to shorter term fluctuations in glucose concentrations . 
Some glycated hemoglobin methods are affected by hemoglobin variants . 
Fructosamine is not subject to this interference . 

                             Indication 

Evaluate diabetic control 

Interpretation 

Increased in  : Diabetic patients  with poor 
                        glucose control 
Decreased in : Sever hypoproteinemia 



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