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Glycated Hemoglobin A1c

Glycated Hemoglobin A1c

Synonyms - Specimen - Reference Value -Method
- Description - Indications - Interpretation 



Synonyms           : Hemoglobin A1c , A1c 
Specimen              :  Whole blood (1mL) collected in 
                                EDTA tube . 
Reference  Value : Total A1 4.0 - 7.0% , A1c 4.0 -5.5 % 
Method                : Chromatography 


Description 

Glycosylated or Glycated hemoglobin is a term used to describe the combination of glucose and hemoglobin into a ketamine , the rate at which this occurs in proportional to glucose concentration . The average life span of a red blood cells is approximately 120 days ; measurements of glycated hemoglobin is a way to monitor  long - term diabetic management .
Hemoglobin A1c levels are not age dependent and are not affected by exercise , diabetic medications , or non fasting   state before specimen collection 

Indications 
Assess long-term glucose control in diabetics 

Interpretations 

Increase in : 

Diabetes ( Poorly controlled or uncontrolled ) 

Decreased in 

- Chronic blood loss 
- Chronic renal failure 
- Conditions that decrease red blood cell life span 
- Hemolytic  anemia 





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