Glycated Hemoglobin A1c

Ehab Ali Maher

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Glycated Hemoglobin A1c

Synonyms - Specimen - Reference Value -Method

- Description - Indications - Interpretation

Synonyms : Hemoglobin A1c , A1c

Specimen : Whole blood (1mL) collected in

EDTA tube .

Reference Value : Total A1 4.0 - 7.0% , A1c 4.0 -5.5 %

Method : Chromatography

Description

Glycosylated or Glycated hemoglobin is a term used to describe the combination of glucose and hemoglobin into a ketamine , the rate at which this occurs in proportional to glucose concentration . The average life span of a red blood cells is approximately 120 days ; measurements of glycated hemoglobin is a way to monitor long - term diabetic management .

Hemoglobin A1c levels are not age dependent and are not affected by exercise , diabetic medications , or non fasting state before specimen collection

Indications

Assess long-term glucose control in diabetics

Interpretations

Increase in :

Diabetes ( Poorly controlled or uncontrolled )

Decreased in

- Chronic blood loss

- Chronic renal failure

- Conditions that decrease red blood cell life span

- Hemolytic anemia

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