INTRODUCTION OF TUMOR MARKERS
Cancer is a word used to describe a condition characterized by spreading destruction of any kind
Cancer is the name given to a group or diseases associated with the development , growth , and spread of destructive overgrowth of tissue , called Malignant tumor or neoplasm , in living organism
A tumor is benign when it is restricted to its primary site and malignant when it is capable of invading surrounding tissue.
Malignant Tumors
these are invasive , destruction and associated with a generally poor prognosis and high mortality rate
Malignant tumors growth may occur at any site in the organism and may spread in time to other sites .
Pathogenesis of the disease is largely due to
a- Obstruction and destruction of other vital structures in the body
b - Functional activity of a substance produced by the tumor .
c - Bleeding
d - Infection
e - Toxic substances associated with infarction and necrosis
The major difference between normal cells and tumor cells is that growth control has been lost in tumor cells .
Neoplastic transformation is associated with altered gene expression , which may affect production of enzymes , hormones , receptors , protein and metabolites that are released into the circulatory system .
These substances , if they can be measured and in the diagnosis and characterization of disease and have potential use in the treatments and cure of cancers .
This group of substances has come to be known as Tumor markers .
Comments
Post a Comment