Sickle cell anemia is an inherited blood disease in which
the red blood cells produce abnormal pigment (hemoglobin). The abnormal
hemoglobin causes deformity of the red blood cells into crescent or
sickle-shapes, as seen in this photomicrograph.
Red blood cells, elliptocytosis
Elliptocytosis is a hereditary disorder of the red blood
cells (RBCs). In this condition, the RBCs assume an elliptical shape, rather
than the typical round shape.
Red blood cells, spherocytosis
Spherocytosis is a hereditary disorder of the red blood
cells (RBCs), which may be associated with a mild anemia. Typically, the
affected RBCs are small, spherically shaped, and lack the light centers seen in
normal, round RBCs.
Red blood cells, multiple sickle cells
Sickle cell anemia is an inherited disorder in which
abnormal hemoglobin (the red pigment inside red blood cells) is produced. The
abnormal hemoglobin causes red blood cells to assume a sickle shape, like the
ones seen in this photomicrograph.
Ovalocytoses
Red blood cells (RBCs) are normally round. In
ovalocytosis, the cells are oval. Other conditions that produce abnormally
shaped RBCs include spherocytosis and eliptocytosis.
Red blood cells, sickle cells
These crescent or sickle-shaped red blood cells (RBCs)
are present with Sickle cell anemia, and stand out clearly against the normal
round RBCs. These abnormally shaped cells may become entangled and block blood
flow in the small blood vessels (capillaries).
Red blood cells, sickle and pappenheimer
This photomicrograph of red blood cells (RBCs) shows both
sickle-shaped and pappenheimer bodies.
Red blood cells, target cells
These abnormal red blood cells (RBCs) resemble targets.
These cells are seen in association with some forms of anemia, and following
the removal of the spleen (splenectomy).