Skip to main content

Gestational Diabetes

A woman has gestational diabetes when she is pregnant and has any two of the following: fasting plasma glucose of more than 105 mg/dl, a 1-hour glucose level of more than 190 mg/dl, a 2-hour glucose level of more than 165 mg/dl, or a 3-hour glucose level of more than 145 mg/dl. 

 

 

 

Fasting  blood glucose

From 70 to 99 mg/dL (3.9 to 5.5 mmol/L)

Normal glucose  tolerance

From 100 to 125 mg/dL (5.6 to 6.9 mmol/L)

Impaired fasting glucose  (pre-diabetes)

126 mg/dL (7.0 mmol/L) and above on more than one testing occasion

Diabetes

 

Oral  glucose Tolerance Test (OGTT)
[except pregnancy]

(2 hours after a 75-gram  glucose drink)

Less than 140 mg/dL (7.8 mmol/L)

Normal  glucose tolerance

From 140 to 200 mg/dL (7.8 to 11.1 mmol/L)

Impaired  glucose tolerance (pre-diabetes)

Over 200 mg/dL (11.1 mmol/L) on more than one testing occasion

Diabetes

 

Gestational Diabetes Screening:  glucose Challenge Test
(1 hour after a 50-gram  glucose drink)

Less than 140* mg/dL (7.8 mmol/L)

Normal  glucose tolerance

140* mg/dL (7.8 mmol/L) and over

Abnormal, needs OGTT (see below)

* Some use a cutoff of >130 mg/dL (7.2 mmol/L) because that identifies 90% of women with gestational diabetes, compared to 80% identified using the threshold of >140 mg/dL (7.8 mmol/L).

 

Gestational Diabetes Diagnostic: OGTT
(100-gram glucose  drink)

Fasting*

95 mg/dL (5.3 mmol/L)

1 hour after  glucose load*

180 mg/dL (10.0 mmol/L)

2 hours after  glucose load*

155 mg/dL (8.6 mmol/L)

3 hours after glucose  load* **

140 mg/dL (7.8 mmol/L)

* If two or more values are above the criteria, gestational diabetes is diagnosed.
** A 75-gram glucose load may be used, although this method is not as well validated as the 100-gram OGTT; the 3-hour sample is not drawn if 75 grams is used.

 

What Affects the Test? 

 

Reasons you may not be able to have the test or why the results may not be helpful include:

  • Eating or drinking less than 8 hours before a fasting blood test or less than 2 hours before a 2-hour postprandial test.

  • Drinking alcohol.

  • Illness or emotional stress, smoking, and caffeine.

Comments

Popular posts from this blog

MICROSCOPIC URINALYSIS

MICROSCOPIC URINALYSIS   Methodology A sample of well-mixed   urine (usually 10-15 ml) is centrifuged in a test tube at relatively low speed (about 2-3,000 rpm) for 5-10 minutes until a moderately cohesive button is produced at the bottom of the tube. The supernatant is decanted and a volume of 0.2 to 0.5 ml is left inside the tube. The sediment is resuspended in the remaining supernatant by flicking the bottom of the tube several times. A drop of resuspended sediment is poured onto a glass slide and coverslipped.

Liver Enzymes

Liver Enzymes   Definition A liver enzyme is a protein that helps to speed up a chemical reaction in the   liver. Liver function tests are blood tests that are used to evaluate various functions of the liver - for example, metabolism, storage, filtration and excretion, which are often performed by liver enzymes. However, not all liver function tests are measures of enzyme function. • ALT - (alanine aminotransferase )   - was previously called SGPT is more specific for liver damage. The ALT is an enzyme that is produced in the liver cells (hepatocytes) therefore it is more specific for liver disease than some of the other enzymes. It is generally increased in situations where there is damage to the liver cell membranes. All types of liver inflammation can cause raised ALT.    • AST - (aspartate aminotransferase) which was previously called SGOT. This is a mitochondrial enzyme that is also present in heart, muscle, kidney and brain ...

Gamma globulins

Gamma globulins   Increased in immunoglobulins are often referred to as hyper gammaglobulinemia or gammopathies  Hypogammaglobulinemia This most often results from  decreased synthesis , but could also be associated with increased loss .  1 - Decreased synthesis ( High A : G ratio )  a- failure of passive transfer or colostrum deprivation  b - Combined immunodeficiency disease ( Both T & B cells are deficient )  c - Agammaglobulinemia  d - Acquired deficiency associated with inflammation , immunosuppressive drugs or neoplasia