1 - Ineffective erythropoiesis (thalassemias, sideroblastic)
2 - Intra-vascular hemolysis
3 - Liver disease (alcohol, portocaval shunts)
4 - Excessive iron intake
Causes of Decreased
Iron deficiency
(low ferritin level; nutritional, blood loss, ,
small bowel disease, increased demand)
Chronic disease (liver dysfunction, renal dysfunction, etc.)
Discussion
Iron
is known for its relationship to hemoglobin, which transports oxygen. Confirm true iron deficiency
before supplementing iron. Never give Iron to someone who has an inflamed
liver because this can be toxic. With B<sub>12 or Iron deficiencies, give special
consideration to increased occurrence in the elderly. The most important
test for iron is the serum ferritin.