Glycosylated hemoglobin, commonly known as hemoglobin A1c or simply A1c, is a type of hemoglobin that has glucose molecules attached to it. Red blood cells contain a protein called hemoglobin, which transports oxygen throughout the body.
insulin resistance Insulin resistance is a physiological condition in which cells throughout the body, particularly muscle, liver, and adipose (fat) tissue, become less responsive to the effects of insulin. Insulin is a hormone produced by the pancreas that plays a crucial role in regulating blood sugar (glucose) levels. It helps cells take up glucose from the bloodstream, allowing the body to use it for energy or store it for later use. When cells become insulin resistant, they don't respond as effectively to insulin's signals, and as a result, they don't take up glucose from the blood efficiently. This leads to higher levels of glucose remaining in the bloodstream, a condition known as hyperglycemia. In response to this, the pancreas often produces more insulin to try to overcome the resistance and control blood sugar levels. This increased insulin production can lead to elevated insulin levels in the blood (hyperinsulinemia).